Browsing by Subject "multiple sclerosis"
Now showing items 1-2 of 2
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DEVELOPMENT OF BUTYRYLCHOLINESTERASE LIGANDS FOR THE IMAGING OF NEUROLOGICAL DISORDERS
(2013-08-12)Butyrylcholinesterase (BuChE) is a serine hydrolase enzyme that, along with acetylcholinesterase (AChE), catalyzes the hydrolysis of acetylcholine. These enzymes are associated with the pathology of neurologic disorders ... -
The roles of cellular Inhibitor of Apoptosis Protiens 1 and 2 in the polarization of M1 and M2 macrophages
This thesis examined the effects of genetic ablation of the anti-apoptotic protein cIAP2 and SMAC mimetic (LCL161)-induced cIAP1 and cIAP2 suppression on the polarization of pro-inflammatory (M1) and anti-inflammatory (M2) ...