Browsing by Subject "cardiovascular disease"

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BRIDGING THE GAP BETWEEN BASIC SCIENCE AND CLINICAL TRANSLATION: UNDERSTANDING THE ASSOCIATIONS BETWEEN MONOCYTES/MACROPHAGES AND INFLAMMATION IN PATIENTS UNDERGOING CARDIAC SURGERY

Gawdat, Kareem

Cardiovascular disease (CVD) is the leading cause of death worldwide. Work from our lab group and others has shown that monocytes/macrophages are key mediators in the inflammatory response involved in CVD and the development ...
MODULATION OF APOLIPOPROTEIN B-100 DEGRADATION AND SECRETION BY HEPATIC PROTEIN QUALITY CONTROL COMPONENTS

Fisher, Eric Alexander (2015-04-28)

The central protein component of hepatic very low density lipoproteins (VLDL), apolipoprotein B-100 (apoB-100), is unique in that it is removed via endoplasmic reticulum-associated degradation (ERAD) when poorly lipidated. ...